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Learn from the experts

The following videos present some of the advances and research into pre-eclampsia and its diagnosis.

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Mrs Shonagh Haslam
Implementation of pre-eclampsia markers, insight into assay performance and clinical models.

Shonagh Haslam is a Principal Clinical Biochemist at Lancashire Teaching Hospitals NHS Foundation Trust, Royal Preston Hospital, UK and is an honorary lecturer at Manchester University. Her main interests include the use of pre-analytics and automation and she has a keen interest in both immunoassay and endocrinology, having published in this field. Additionally, Shonagh is a regional Clinical Champion through the NHS Innovation Agency for pre-eclampsia markers and as an early adopter site is able to support other sites with their test introduction. In November 2020 Shonagh became a Specialist Committee Member on the Diagnostics Advisory Committee for the update of DG23 (PlGF -based testing to help diagnose suspected pre-eclampsia). Clinically one of her particular interests is to define novel roles for Clinical Scientists in providing patient facing services. She jointly runs weekly lipid clinics with other Clinical Scientists and Endocrinologists. She is also an active member of the Association of Clinical Biochemistry Scientific Committee. 

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Professor Jenny Myers 
Implementation of PIGF -based testing: experience from the Greater Manchester region.
Jenny Myers is Professor of Obstetrics & Maternal Medicine within the Maternal & Fetal Health Research Centre, University of Manchester and Consultant Obstetrician, St Mary’s Hospital. As an obstetrician, Jenny works on the labour ward of this busy tertiary unit
(>9000 deliveries), leads the diabetic, renal and hypertension service and runs two translational research clinics for women with hypertension and diabetes. She currently leads a portfolio of clinical and laboratory science studies which spans vascular and placental biology research, preclinical models, observational cohort studies and intervention trials before, during and after pregnancy. Jenny is also the lead site investigator for several multicenter studies related to hypertension and diabetes in pregnancy. Jenny chairs the North West p
re-eclampsia Guideline Group, is the Maternal Medicine representative for the British Maternal & Fetal Medicine Society, is a Consulting Editor for Plos Medicine, President of the RCOG Blair Bell Research Society and has served on several NICE committees.
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Miss Amy Kiley
Implementation of pre-eclampsia markers: Insight into the laboratory practicalities.
Amy Kiley is a Clinical Biochemist at Doncaster & Bassetlaw Teaching Hospitals, where she is responsible for leading the Special Chemistry & Immunology sections. Amy led the laboratory implementation of sFlt-1/PlGF ratio testing on the Roche cobas e 411 analyser, working in collaboration with clinical colleagues in maternity services on the two hospital sites. 
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Dr Sofia Cerdeira

Assessment of pre-eclampsia using sFlt-1/PIGF: a change in clinical practice at the John Radcliffe Hospital. 

Sofia Cerdeira is a Clinician Scientist with a focused interest in pre-eclampsia and angiogenic factors. Sofia graduated in Medicine (University of Porto, Portugal) in 2003 and moved to Harvard Medical School to pursue research in pre-eclampsia. After completing her PhD in 2014, Sofia joined the University of Oxford in a combined academic and clinical position conducting research in angiogenic biomarkers test and pioneered the introduction of the diagnostic test in clinical practice in Oxford together with Manu Vatish and Tim James. The Oxford group is supporting its implementation in hospitals throughout the United Kingdom and abroad. Sofia has published more than 40 basic science and clinical papers on pre-eclampsia. 

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Toni Brunt

PlGF- based testing at Doncaster & Bassetlaw Teaching Hospitals for the assessment of pre-eclampsia.

Toni graduated from Northumbria University in 2011. During her 10 years' experience as a Midwife she has worked within various areas of maternity, including a managerial role. Toni has led the implementation of PlGF based testing for the assessment of pre-eclampsia at Doncaster & Bassetlaw Teaching Hospitals and is the midwifery lead for ongoing PReCePT work and the implementation of the QUiPP app within the trust.
Toni is currently completing a QI coach qualification and is passionate about promoting positive change and improved care for women and families.

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Speakers at the Preeclampsia Symposium

Professor Manu Vatish 

Manu Vatish is Professor of Obstetrics at the University of Oxford and consultant obstetrician at the John Radcliffe Hospital in Oxford. He runs two research groups, one looking at the basic science of placental function, and the other examining the effects of angiogenic biomarkers on pre-eclampsia diagnosis and management. He is also clinical director for the NIHR CRN for the Thames Valley and South Midlands and is academic programme training director for the Oxford University Clinical Academic Graduate School.

Professor Jenny Myers

Jenny Myers is Professor of Obstetrics & Maternal Medicine within the Maternal & Fetal Health Research Centre, University of Manchester and Consultant Obstetrician, St Mary’s Hospital. As an obstetrician, Jenny works on the labour ward of this busy tertiary unit (>9000 deliveries), leads the diabetic, renal and hypertension service and runs two translational research clinics for women with hypertension and diabetes. She currently leads a portfolio of clinical and laboratory science studies which spans vascular and placental biology research, preclinical models, observational cohort studies and intervention trials before, during and after pregnancy. Jenny is also the lead site investigator for several multicenter studies related to hypertension and diabetes in pregnancy. Jenny chairs the North West Pre-eclampsia Guideline Group, is the Maternal Medicine representative for the British Maternal & Fetal Medicine Society, is a Consulting Editor for Plos Medicine, President of the RCOG Blair Bell Research Society and has served on several NICE committees.

Mrs Shonagh Haslam

Shonagh Haslam is a Principal Clinical Biochemist at Lancashire Teaching Hospitals NHS Foundation Trust, Royal Preston Hospital, UK and is an honorary lecturer at Manchester University. Her main interests include the use of pre-analytics and automation and she has a keen interest in both immunoassay and endocrinology, having published in this field. Additionally, Shonagh is a regional Clinical Champion through the NHS Innovation Agency for pre-eclampsia markers and as an early adopter site is able to support other sites with their test introduction. In November 2020 Shonagh became a Specialist Committee Member on the Diagnostics Advisory Committee for the update of DG23 (PlGF-based testing to help diagnose suspected pre-eclampsia). Clinically one of her particular interests is to define novel roles for Clinical Scientists in providing patient facing services. She jointly runs weekly lipid clinics with other Clinical Scientists and Endocrinologists. She is also an active member of the Association of Clinical Biochemistry Scientific Committee.

Miss Amy Kiley

Amy Kiley is a Clinical Biochemist at Doncaster & Bassetlaw Teaching Hospitals, where she is responsible for leading the Special Chemistry & Immunology sections. Amy led the laboratory implementation of sFlt-1/PlGF ratio testing on the Roche e411, working in collaboration with clinical colleagues in maternity services on the two hospital sites.

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