CINtec PLUS Cytology provides a triage solution that informs better risk stratification for HPV-positive screening results3.
Not every HPV-positive woman will develop Cervical Cancer, so triage can determine who is most at risk and will benefit from more immediate follow-up, and who is at low risk and can be given more time to clear the infection on her own. CINtec PLUS is a triage cytology test that helps stratify disease risk immediately, giving clinicians confidence when selecting the appropriate management for women at every level of risk.
CINtec PLUS Cytology has dual-biomarker technology for more definitive results.
It’s not enough to know that a patient is positive for HPV, but whether HPV is causing changes at the cellular level. CINtec PLUS Cytology is available in Australia for patients with positive high risk HPV results.
It is a test that uses dual-biomarker technology to simultaneously detect p16 and Ki-67 in women with HPV-positive results.
The co-expression of these two biomarkers is a strong indicator that an HPV infection is undergoing oncogenic transformation.
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*For HPV16/18+ use as additional information in conjunction with the physician’s assessment of patient screening history, other risk factors, and professional guidelines to guide patient
management. hr = high risk
References:
1. Walmers JM, Jacobs MV, Manos MM, et al. Human papillomavirus is a necessary cause of invasive cervical cancer worldwide. J Pathol. 1999;189:12-19.
2. CINtec PLUS Cytology [package insert]. Tucson, AZ: Ventana Medical Systems, Inc.; 2020. Data from the IMPACT trial.
3. Wright TC, et al. Clinical validation of p16/Ki-67 dual-stained cytology triage of HPV-positive women: Results from the IMPACT trial. IJC. 2022;150(3):461-471.
THESE PRODUCTS ARE NOT AVAILABLE FOR PURCHASE BY THE GENERAL PUBLIC.
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Published by: Roche Diagnostics Australia Pty Limited.
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